Enbrel 50mg Injection contains Etanercept, a biologic medication used primarily in the treatment of autoimmune diseases. It is an inhibitor of tumor necrosis factor (TNF) that aids in immune response modulation and inflammation reduction.

Brand Name: Enbrel

Composition: Etanercept

Mechanism of Action:

TNF, a pro-inflammatory cytokine implicated in systemic inflammation, is bound by etanercept, a soluble TNF receptor. Intacept helps to lower inflammation and the immune system's overall response by blocking TNF activity, which lessens the symptoms of autoimmune disorders.

Uses:

• Rheumatoid Arthritis
• Psoriatic Arthritis
• Ankylosing Spondylitis
• Crohn's Disease
• Ulcerative Colitis

Dosage and Administration:

The disease being treated and the patient's reaction determine the amount and frequency of administration. Usually, it can be injected subcutaneously, with maintenance doses given at predetermined intervals after the initial dose.

Side Effects:

·       Nausea

·       Vomiting

·       Diarrhea

·       Dizziness

·       Fever

·       Rash

·       Headache

·       Allergic reactions

·       Seizures

·       Thrombocytosis

Safety Advise:

Kidney  

Dose adjustments are required in patients with renal impairment. Kindly speak with your healthcare provider.

Liver  

Liver function tests should be monitored during prolonged treatment, especially in patients with liver disease. Kindly speak with your healthcare provider.

Pregnancy  

Use Enbrel during pregnancy only if clearly needed and under medical supervision, as its safety during pregnancy is not fully established.  Kindly speak with your healthcare provider.

Breast Feeding  

Caution is advised during breastfeeding since the drug can pass into breast milk. Kindly speak with your healthcare provider.

Driving  

Your ability to drive may be impacted by adverse effects from Enbrel Injection. Kindly speak with your healthcare provider.

Storage:

Store Enbrel Injection in the refrigerator (2-8°C) and protect it from light. It should not be frozen.

How to use this medication?

The drug is administered subcutaneously. You'll learn how to prepare and administer it. Follow the instructions on the medicine label. Until your care team instructs you to stop, continue taking it.

Make careful to remove the outer needle cover from the pen before administering the dosage. 

It's crucial to store used syringes and needles in a designated sharps container. Keep them out of the garbage can. Get a sharps container by calling your care team or pharmacist if you don't already have one.

References:

1.      Jarvis B, Faulds D. Etanercept: a review of its use in rheumatoid arthritis. Drugs. 1999 Jun;57:945-66.

2.      Ducharme E, Weinberg JM. Etanercept. Expert Opinion on Biological Therapy. 2008 Apr 1;8(4):491-502.

3.      Goffe B, Cather JC. Etanercept: an overview. Journal of the American Academy of Dermatology. 2003 Aug 1;49(2):105-11.

4.      Zhao S, Mysler E, Moots RJ. Etanercept for the treatment of rheumatoid arthritis. Immunotherapy. 2018 Feb 27;10(6):433-45.

Disclaimer:

The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Pfizer Ltd

Address: The Capital, 1802, 18th Floor, Plot No. C-70, ‘G’ Block, Bandra Kurla Complex, Bandra East, Mumbai – 400051.

Country of origin: India