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Dasanat 50 mg Tablet contains the active ingredient dasatinib, a type of chemotherapy drug known as a tyrosine kinase inhibitor. It is mostly used to treat leukemias that are positive for the Philadelphia chromosome (Ph+), such as Acute lymphoblastic leukemia and Chronic Myeloid leukemia.
Inform your healthcare provider about all medications you're using, since interactions may occur. Steer clear of using it if you are pregnant or nursing, and if you feel lightheaded or have blurred vision, don't drive.
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Dasanat 50 mg Tablet contains the active ingredient dasatinib, a type of chemotherapy drug known as a tyrosine kinase inhibitor. It is mostly used to treat leukemias that are positive for the Philadelphia chromosome (Ph+), such as Acute lymphoblastic leukemia and Chronic Myeloid leukemia.
Brand Name: Dasanat
Composition: Dasatinib
Mechanism of Action:
Dasatinib functions by blocking a number of tyrosine kinases that are essential for cancer cells to proliferate and survive. It specifically targets the BCR-ABL protein, which is generated in Acute lymphoblastic leukemia (ALL) and Chronic Myeloid leukemia (CML) as a result of the abnormal Philadelphia chromosome. Dasatinib inhibits this protein, which stops cancer cells from proliferating and causes them to die.
Uses:
Acute lymphoblastic leukemia (ALL)
Chronic Myeloid leukemia (CML)
Dosage and Administration:
Dasatinib dosage is decided by the condition being treated and the patient's reaction to treatment. Tablets should be swallowed whole, with or without food. To prevent the drug from entering your body through your skin, do not break or shatter the tablets.
Side Effects:
Safety Advise:
Kidney 
Kidney function tests should be conducted periodically, as dasatinib can cause renal toxicity. Kindly speak with your Healthcare Provider.
Liver
Liver function tests should be conducted periodically, as dasatinib can cause hepatic toxicity. Kindly speak with your Healthcare Provider.
Pregnancy
As dasatinib may harm the fetus, it is not advised to use it during pregnancy. During therapy, women who are or may get pregnant should take an effective form of contraception. Kindly speak with your Healthcare Provider.
Breast Feeding
It is not safe to use Dasanat 50 Tablet during nursing. Evidence points to the possibility of medication poisoning in the fetus. Kindly speak with your Healthcare Provider.
Alcohol
It is unknown whether it is safe to take alcohol with Dasanat 50 Tablet. Kindly speak with your Healthcare Provider.
Driving
Your ability to drive may be impacted by adverse effects from Dasanat 50 Tablet. In the case that Dasanat 50 Tablet side effects include dizziness or blurred vision, drive carefully.
Storage:
Store at room temperature (15°C - 30°C), away from moisture and direct sunlight. Keep the medication out of reach of children.
How to use this Medication?
Take this medicine by mouth with water, following the prescription label, and avoid grapefruit juice. Do not cut or crush it, and avoid antacids or other acid-reducing medicines within 2 hours of taking this medication.
Consult your pediatrician about the usage of this medication in young patients. Although this medication may be administered for specific diseases in children as young as one year old, there are some things to keep in mind.
1. Nuli MV, Rekulapally VK. Overall review on analytical method development and validation of Dasatinib. International Journal of Pharmacognosy and Chemistry. 2023 Mar 31:27-34.
2. Lindauer M, Hochhaus A. Dasatinib. Small Molecules in Oncology. 2014 Apr 23:27-65.
3. Kantarjian H, Jabbour E, Grimley J, Kirkpatrick P. Dasatinib. Nature reviews Drug discovery. 2006 Sep 1;5(9).
4. Aguilera DG, Tsimberidou AM. Dasatinib in chronic myeloid leukemia: a review. Therapeutics and Clinical Risk Management. 2009 May 4:281-9.
Disclaimer:
The main goal of Apothecare Wellness is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Wellness, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.
Marketer details
Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India
Country of origin: India