Ibrunat 140mg Capsule contains Ibrutinib, a Bruton’s Tyrosine Kinase (BTK) inhibitor used primarily in the treatment of certain types of blood cancers.

Brand Name: Ibrunat

Composition: Ibrutinib

Mechanism of Action:

Bruton's Tyrosine Kinase (BTK), a protein essential to B cell survival and proliferation, is inhibited by imatinib. Ibrutinib stops B cells from getting survival signals by blocking BTK, which causes B cells to die and slows the growth of cancer cells.

Uses:

• Chronic Lymphocytic Leukemia
• Mantle Cell Lymphoma
• Waldenstrom’s Macroglobulinemia
• Marginal Zone Lymphoma
• Chronic Graft vs Host Disease: A condition where the immune cells in transplanted bone marrow attack the recipient's body.

Dosage and Administration:

Depending on the type of cancer being treated, different Ibrutinib dosages may be required. taken orally, at the same time every day, once a day. Take a glass of water and swallow the capsules whole. Avoid chewing or crushing the capsules.

Side Effects:

• Diarrhea
• Fatigue
• Nausea
• Muscle pain
• Bruising
• Decreased platelets
• Upper respiratory infections
• Hypertension
• Tumor Lysis Syndrome

Safety Advise:

Kidney    

Patients with renal illness should use Ibrunat 140mg Capsule with caution. Kindly speak with your healthcare provider.

Liver    

Patients with hepatic condition should use Ibrunat 140mg Capsule with caution. Kindly speak with your healthcare provider.

Heart  

Patients with a history of heart issues should have their arrhythmias checked. Kindly speak with your healthcare provider.

Pregnancy  

Ibrutinib may cause harm to a fetus. Effective contraception must be utilized during treatment, and it should not be used during pregnancy unless absolutely essential. Kindly speak with your healthcare provider.

Breastfeeding  

Breastfeeding is not advised while taking Ibrutinib because of possible dangers to the infant. Kindly speak with your healthcare provider.

Alcohol    

Avoiding alcohol or consuming it in moderation is advised because it might worsen side effects including nausea and interfere with liver function.

Storage:

Store at room temperature (20°C to 25°C) in a dry place, away from moisture and direct sunlight. Keep out of reach of children.

How to use this Medication?

Take this medication orally, without crushing or chewing, at the same time every day with water. When your care team advises you to stop taking a medicine because of adverse effects or adjust the dosage, do as directed.

Avoid consuming grapefruit juice or Seville oranges while taking this medication.

Discuss the usage of this drug in children with your care team. Precautions do apply, even though it can be administered to infants as young as one year old for specific conditions. 

Overdosage: Contact an emergency department or poison control center right away if you believe you may have taken too much of this medication.

Disclaimer:

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