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Leucorin 50mg Injection contains Leucovorin Calcium is used to stop the negative effects of the anticancer drug methotrexate. Additionally, it is used to treat methotrexate overdose.
As directed by your physician, you should take it precisely as prescribed. Serious negative effects might result from taking it incorrectly or in excess.
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Leucorin 50mg Injection contains Leucovorin Calcium is used to stop the negative effects of the anticancer drug methotrexate. Additionally, it is used to treat methotrexate overdose.
Brand Name: Leucorin
Composition: Leucovorin Calcium
Leucorin is one active form of folic acid. It avoids the metabolic block caused by methotrexate, which prevents the production of nucleotides required for DNA synthesis and repair by inhibiting the enzyme dihydrofolate reductase. This lessens the negative effects of methotrexate on healthy cells.
Methotrexate Rescue
Depending on the therapeutic circumstance, leucorin is usually given intravenously. The chemotherapy regimen and the ailment being treated determine the dosage and timing of treatment.
Lungs 
The safety of Leucorin Injection for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.
Liver
The safety of Leucorin Injection for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.
Kidney
The safety of Leucorin Injection for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.
Pregnancy
Leucorin should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.
Breast Feeding
Using Leucorin while nursing is most likely dangerous. Kindly speak with your healthcare provider.
Storage in 2-8 °C, do not freeze. Keep away from children and place away from sun light.
As directed by your physician, this drug is injected into a vein or muscle once daily or usually every six hours. It should not be injected into the spine.
Your medical condition and reaction to therapy will determine the dosage. Use it frequently for best results. If using at home, make sure you follow your doctor's preparation and usage guidelines and look for any particles or discolouration before using. Learn how to properly store and dispose of medical items as well.
Contact an emergency department or poison control center right away if you believe you have taken too much of this medication.
It is mainly used for methotrexate rescue and management of methotrexate toxicity or overdose.
Leucovorin provides reduced folate to healthy cells, helping protect them from the effects of folate-blocking medicines.
It uses Leucovorin after high-dose Methotrexate to help reduce toxicity to healthy cells.
No. Leucorin is Leucovorin Calcium (folinic acid) and is mainly used as rescue or supportive therapy.
Yes. Leucovorin may be combined with 5-fluorouracil (5-FU) in certain cancer treatment regimens.
It is administered by a healthcare professional according to the prescribed treatment or rescue protocol.
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