Sovihep V Tablet is a combination antiviral medication primarily used in the treatment of chronic hepatitis C infection. It comprises Velpatasvir and Sofosbuvir, which together prevent the hepatitis C virus (HCV) from replicating.

Brand Name: Sovihep V

Composition: Sofosbuvir, Velpatasvir

Mechanism of Action:

By inhibiting the viral RNA polymerase, sofosbuvir, an NS5B polymerase inhibitor, stops the virus from replicating. Velpatasvir is an NS5A inhibitor that prevents the hepatitis C virus from replicating and assembling.

Uses:

Chronic Hepatitis C Infection

Dosage and Administration:

One tablet taken once a day, with or without food, is the usual dosage. The length of treatment varies from 12 to 24 weeks, depending on the virus's genotype and past treatment history.

Side Effects:

• Fatigue
• Headache
• Nausea
• Vomiting
• Fever
• Cough
• Insomnia
• Liver Function Abnormalities
• Allergic Reactions

Safety Advise:

Kidney  

Monitor kidney function regularly, as sovihep can cause nephrotoxicity. Kindly speak with your healthcare provider.

Liver  

Monitor liver function regularly, as sovihep can cause liver impairement. Kindly speak with your healthcare provider.

Pregnancy  

Sovihep should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.

Breast Feeding  

Using sovihep while nursing is most likely dangerous. Kindly speak with your healthcare provider.

Alcohol  

Sovihep should not be taken with alcohol. Kindly speak with your healthcare provider.

Storage:

Store Sovihep Tablet at a temperature between 15°C and 30°C (59°F to 86°F). Keep the tablets in the original packaging to protect them from light and moisture. Keep out of reach of children.

References:

1.      Greig SL. Sofosbuvir/velpatasvir: a review in chronic hepatitis C. Drugs. 2016 Oct;76(16):1567-78.

2.    Foster GR, Afdhal N, Roberts SK, Bräu N, Gane EJ, Pianko S, Lawitz E, Thompson A, Shiffman ML, Cooper C, Towner WJ. Sofosbuvir and velpatasvir for HCV genotype 2 and 3 infection. New England Journal of Medicine. 2015 Dec 31;373(27):2608-17.

3.      Jackson WE, Everson GT. Sofosbuvir and velpatasvir for the treatment of hepatitis C. Expert review of gastroenterology & hepatology. 2017 Jun 3;11(6):501-5.

4.    Pianko S, Flamm SL, Shiffman ML, Kumar S, Strasser SI, Dore GJ, McNally J, Brainard DM, Han L, Doehle B, Mogalian E. Sofosbuvir plus velpatasvir combination therapy for treatment-experienced patients with genotype 1 or 3 hepatitis C virus infection: a randomized trial. Annals of internal medicine. 2015 Dec 1;163(11):809-17.

Disclaimer:

The main goal of Apothecare Specialities Pvt Ltd is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Specialities Pvt Ltd, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Zydus Life Sciences

Address: Zydus Corporate Park, Scheme No.63, Survey No. 536, Khoraj (Gandhinagar), Nr. Vaishnodevi Circle, Sarkhej - Gandhinagar High, Ahmedabad, Gujarat, India-382481

Country of origin: India 

Frequently Asked Questions (FAQs):

1. What is Sovihep V Tablet?

Sovihep V Tablet is a combination antiviral medication containing Sofosbuvir and Velpatasvir. It may be prescribed for the management of chronic hepatitis C virus (HCV) infection.

2. How may Sovihep V work?

It is believed to inhibit specific viral proteins (NS5B and NS5A), which may potentially disrupt the replication of the hepatitis C virus within the body.

3. Which HCV genotypes may it treat?

It may potentially be effective against all major genotypes (1-6) of the hepatitis C virus in adults.

4. How is Sovihep V typically taken?

It is generally taken orally as one tablet once a day.

5. Can it be taken with food?

It may typically be taken with or without food, as directed by your healthcare provider.

6. What are the possible side effects?

Patients may potentially experience headache, fatigue, nausea, or insomnia.

7. Does it cure Hepatitis C?

While it may help clear the virus from the blood in many patients after completing the course, individual outcomes vary, and it is not guaranteed.

8. Are there significant drug interactions?

Yes, it may potentially interact with certain antacids, anti-seizure medications, and amiodarone, which may require medical monitoring.

9. Can it be used if I have liver cirrhosis?

It may be prescribed for patients with compensated or decompensated cirrhosis, sometimes in combination with other medications like ribavirin, under specialist guidance.

10. How long is the treatment course?

The typical treatment duration may be 12 weeks, though this may vary based on your specific medical condition.

11. Can I stop taking it early if I feel better?

Stopping early may potentially lead to a relapse of the infection; it is advised to complete the full course as prescribed.

12. Is Sovihep V a prescription medicine?

Yes, it is a prescription-only antiviral medication.

Medical Disclaimer:

Sovihep V Tablet is a prescription-only medicine and must be used strictly under the supervision and guidance of a qualified healthcare professional. Do not self-medicate, alter the dosage, or discontinue use without consulting your doctor. The information provided here is for educational purposes only and should not be considered a substitute for professional medical advice, diagnosis, or treatment. Individual results, benefits, and risks may vary. Always consult your physician before starting, changing, or stopping any medication.