Xylistin Forte 2 MIU Injection contains colistimethate sodium, an antibiotic used to treat severe bacterial infections, particularly those caused by multidrug-resistant Gram-negative bacteria.
Brand Name: Xylistin
Composition: Colistimethate sodium
Mechanism of Action:
Colistin interacts with the lipopolysaccharide (LPS) layer of Gram-negative bacterial membranes, increasing membrane permeability. This results in the leakage of intracellular contents and ultimately bacterial death. It is highly effective against multidrug-resistant (MDR) Gram-negative bacteria, including Pseudomonas aeruginosa, Acinetobacter baumannii, and certain Enterobacteriaceae.
Uses:
· Severe Respiratory Infections
· Urinary Tract Infections
· Sepsis/Septicemia
· Intra-abdominal Infections
· Bone and Joint Infections
· Meningitis
Dosage and Administration:
Dosage is usually based on weight and should be determined by a healthcare professional. Xylistin is given by intravenous or intramuscular injection.
Side Effects:
· Dizziness
· Nausea
· Vomiting
· Fever
· Tingling
· Muscle weakness
· Rash
· Itching
· Bronchospasm
· Local Pain at the injection site
Safety Advise:
Allergy 
Patients with a history of hypersensitivity to colistin should avoid this medication. Kindly speak with your healthcare provider.
Kidney 
Colistin can cause nephrotoxicity, so renal function must be regularly monitored. Dose adjustments may be necessary for patients with renal impairment. Kindly speak with your healthcare provider.
Pregnancy 
Using Xylistin 2MIU Injection while pregnant may be dangerous. Kindly speak with your healthcare provider.
Breast Feeding 
Nursing mothers should not get a 2MIU injection of xylistin unless truly necessary. Kindly speak with your healthcare provider.
Alcohol 
Avoid drinking too much alcohol while taking this medication since it may make your drowsiness, dizziness, or tiredness worse. Kindly speak with your healthcare provider.
Storage:
Store below 25°C, protected from moisture. Once reconstituted, use immediately or store in a refrigerator for a short duration.
Disclaimer:
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Marketer details
Name: Cipla Ltd.
Address: Cipla House, Peninsula Business park, Ganpatrao Kadam Marg, Lower Parel, Mumbai - 400013
Country of origin: India
Frequently Asked Questions (FAQs):
1. What is Xylistin 2 MIU Injection used for?
It is used to treat serious bacterial infections caused by multidrug-resistant Gram-negative bacteria.
2. How does Xylistin 2 MIU Injection work?
It kills bacteria by disrupting their outer cell membrane.
3. How is Xylistin 2 MIU Injection administered?
It is given by a healthcare professional through intravenous infusion or inhalation as prescribed.
4. Can Xylistin 2 MIU Injection treat viral infections?
No, it is effective only against bacterial infections only.
5.What are the common side effects of Xylistin 2 MIU Injection?
Kidney function changes, dizziness, tingling, numbness, and injection-site reactions may occur.
6. Can patients with kidney disease use Xylistin 2 MIU Injection?
Yes, but the dose should be adjusted and kidney function monitored by your doctor.
7. Is Xylistin 2 MIU Injection safe during pregnancy?
It should be used during pregnancy only if your doctor considers it necessary.
8. Can Xylistin 2 MIU Injection be used with other antibiotics?
Yes, your doctor may prescribe it along with other antibiotics for severe infections.
9. Should I complete the full course of Xylistin 2 MIU Injection?
Yes, completing the full prescribed course helps prevent antibiotic resistance.
10. What is the doctor's advice before using Xylistin 2 MIU Injection?
Use this medicine only under medical supervision with regular monitoring of kidney function.