Claxnova 100mg Tablet – Uses, Price & Blood Cancer Treatment

Claxnova 100mg Tablet includes Venetoclax is an oral prescription medicine used to treat certain blood malignancies, such as chronic lymphocytic leukemia, small lymphocytic lymphoma, and, when combined with other medications, acute myeloid leukemia in certain patient populations.

Claxnova 100mg Tablet is an anticancer medicine used in the treatment of certain type of cancer. It contains venetoclax and work by interfering with the growth and multiplication of abnormal cells. It should be used only under the supervision of a qualified healthcare professional and according to the prescribed dosage

Brand Name: Claxnova

Composition: Venetoclax

Mechanism of Action:

Venetoclax is a specific inhibitor of the anti-apoptotic protein BCL-2, which is overexpressed in several malignancies. By inhibiting BCL-2, it restores the natural process of programmed cell death (apoptosis), which results in the demise of cancer cells.

Uses of Claxnova 100mg Tablet:

• Chronic lymphocytic leukaemia
• Acute myeloid leukaemia combination with other medications
• small lymphocytic lymphoma.

Dosage and Administration:

Claxnova is taken orally once per day, with food. To prevent tumor lysis syndrome (TLS), the dosage is progressively increased over several weeks. 

Side Effects of Claxnova 100mg Tablet:

•       Low white blood cell counts
•       Neutropenia and thrombocytopenia
•       Nausea​
•       Diarrhea​
•       Anemia​
•       Fatigue​
•       Upper respiratory tract infections​
•       Tumor lysis syndrome

Safety Advise:

Lungs  

The safety of Claxnova Tablet for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.

Liver  

The safety of Claxnova Tablet for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.

Kidney  

The safety of Claxnova Tablet for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.

Pregnancy  

Avoided as can cause fetal harm and effective contraception is recommended while taking this medication

Breast Feeding  

Using Claxnova Tablet while nursing is most likely dangerous. Kindly speak with your healthcare provider. 

Storage:

Keep at room temperature (15-30 °C). Store in a dry place away from moisture and sunlight.

How to use this Medication?

Take this medication orally with food and a glass of water. Follow the instructions on your prescription label. Don't cut, crush, or chew this medication. Do not combine with grapefruit juice or consume Seville oranges or starfruit. Take your medications at regular times. Do not take it more frequently than prescribed. Stop taking only if your doctor advises you to.

The pharmacist will provide you with a unique MedGuide along with each prescription and refill. Make sure to read this material thoroughly each time.

References:

1. Mihalyova J, Jelinek T, Growkova K, Hrdinka M, Simicek M, Hajek R. Venetoclax: A

New wave in hematooncology. Experimental hematology. 2018 May 1;61:10-25.

2. Bose P, Gandhi V, Konopleva M. Pathways and mechanisms of venetoclax resistance.

Leukemia & lymphoma. 2017 Sep 2;58(9):2026-39.

3. Pollyea DA, Amaya M, Strati P, Konopleva MY. Venetoclax for AML: changing the treatment paradigm. Blood advances. 2019 Dec 23;3(24):4326-35.

4. Deeks ED. Venetoclax: first global approval. Drugs. 2016 Jun;76:979-87.

Disclaimer:

The main goal of Apothecare Specialities Pvt Ltd is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Specialities Pvt Ltd, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.

Marketer details

Name: Adley Oncology
Address: SCO-184, Sector – 5, Panchukula – 134114, Haryana (INDIA) 
Country of origin: India

FAQs about Claxnova 100mg Tablet:

1. What is Claxnova used for?

Claxnova is used as prescribed by a healthcare professional for its approved therapeutic indication. 

2. How should Claxnova be taken?

Take Claxnova exactly as directed by your doctor, with or without food as advised. 

3. What are the common side effects of Claxnova?

Side effects vary depending on the active ingredient but may include nausea, headache, or stomach discomfort. 

4. Can I stop taking Claxnova once I feel better?

No, continue taking Claxnova for the prescribed duration unless your doctor advises otherwise. 

5. Are there any precautions before using Claxnova?

Inform your doctor about your medical history, allergies, pregnancy, breastfeeding status, and all other medicines you are taking.