Vendusa 100mg Tablet – Uses, Price & Blood Cancer Treatment
Vendusa 100mg Tablet includes Venetoclax is an oral prescription medicine used to treat certain blood malignancies, such as chronic lymphocytic leukemia, small lymphocytic lymphoma, and, when combined with other medications, acute myeloid leukemia in certain patient populations.
Brand Name: Vendusa
Composition: Venetoclax
Mechanism of Action:
Venetoclax is a specific inhibitor of the anti-apoptotic protein BCL-2, which is overexpressed in several malignancies. By inhibiting BCL-2, it restores the natural process of programmed cell death (apoptosis), which results in the demise of cancer cells.
Uses of Vendusa 100mg Tablet:
- Chronic lymphocytic leukaemia
- Acute myeloid leukaemia
- Small lymphocytic lymphoma (SLL)
Dosage and Administration:
Take venetoclax with food and water, preferably at roughly the same time each day. To prevent tumor lysis syndrome (TLS), the dosage is progressively increased over several weeks.
Side Effects of Vendusa 100mg Tablet:
· Low white blood cell counts (which can increase the risk of infections)
· Nausea
· Diarrhea
· Anemia
· Fatigue
· Upper respiratory tract infections
· Tumor lysis syndrome
Contraindications/Warnings:
Tumour lysis syndrome can be serious and potentially life-threatening, especially when starting treatment. Serious infections and low blood cell counts can occur if not monitored regularly. Drug interactions are very important with venetoclax
Safety Advise:
Lungs
The safety of Vendusa Tablet for individuals with lung issues is uncertain. Kindly speak with your healthcare provider.
Liver
The safety of Vendusa Tablet for individuals with liver issues is uncertain. Kindly speak with your healthcare provider.
Kidney
The safety of Vendusa Tablet for individuals with Kidney issues is uncertain. Kindly speak with your healthcare provider.
Pregnancy
Vendusa Tablet should be used during pregnancy only if clearly needed, Kindly speak with your healthcare provider.
Breast Feeding
Breastfeeding is not recommended during treatment
Storage:
Keep at room temperature (15-30 °C). Store in a dry place away from moisture and sunlight.
How to use this Medication?
Take this medication orally with food and a glass of water. Follow the instructions on your prescription label. Don't cut, crush, or chew this medication. Do not combine with grapefruit juice or consume Seville oranges or starfruit. Take your medications at regular times. Do not take it more frequently than prescribed. Stop taking only if your doctor advises you to.
The pharmacist will provide you with a unique MedGuide along with each prescription and refill. Make sure to read this material thoroughly each time.
References:
1. Mihalyova J, Jelinek T, Growkova K, Hrdinka M, Simicek M, Hajek R. Venetoclax: A New wave in hematooncology. Experimental hematology. 2018 May 1;61:10-25.
2. Bose P, Gandhi V, Konopleva M. Pathways and mechanisms of venetoclax resistance. Leukemia & lymphoma. 2017 Sep 2;58(9):2026-39.
3. Pollyea DA, Amaya M, Strati P, Konopleva MY. Venetoclax for AML: changing the treatment paradigm. Blood advances. 2019 Dec 23;3(24):4326-35.
4. Deeks ED. Venetoclax: first global approval. Drugs. 2016 Jun;76:979-87.
Disclaimer:
The main goal of Apothecare Specialities Pvt Ltd is to make sure that the information it provides to customers is correct, reliable, and reviewed by specialists. This website's contents and information are strictly for informational purposes. They are not meant to be used in place of expert medical advice, diagnosis, or care. Please consult your physician for guidance and ask any questions you may have about any condition or medication. If you read anything on Apothecare Specialities Pvt Ltd, do not discount or delay obtaining competent medical advice. Our goal is to enhance the doctor-patient relationship, not to take its place.
Marketer details
Name: Dr. Reddys Laboratories Limited
Address: Global Distribution centre, Survey No. 41, Bachupally (V), Bachupally (M), Medchal-Malkajgiri(Dist), Hyderabad - 500090
Country of origin: India
FAQs about Vendusa 100mg Tablet:
1. What is Vendusa used for?
Vendusa is used as prescribed by a healthcare professional for its approved therapeutic indication.
2. How should Vendusa be taken?
Take venetoclax WITH FOOD and water, preferably at roughly the same time each day.
3. What are the common side effects of Vendusa?
Side effects vary depending on the active ingredient but may include nausea, headache, or stomach discomfort.
4. Can I stop taking Vendusa once I feel better?
No, continue taking Vendusa for the prescribed duration unless your doctor advises otherwise.
5. Are there any precautions before using Vendusa?
Inform your doctor about your medical history, allergies, pregnancy, breastfeeding status, and all other medicines you are taking.